Rapid Diagnosis and Biomedical Research

Providing a clinically supported service for the rapid diagnosis and management of infectious and genetic disease.

2019

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease

Borghini L, Png E, Binder A, Wright VJ, Pinnock E, de Groot R, Hazelzet J, Emonts M, Van der Flier M, Schlapbach LJ, Anderson S, Secka F, Salas A, Fink C, Carrol ED, Pollard AJ, Coin LJ, Kuijpers TW, Martinon-Torres F, Zenz W, Levin M, Hibberd ML, Davila S; EUCLIDS consortium

Sci Rep. 2019 May 6;9(1):6966 DOI: doi: 10.1038/s41598-019-43292-6

Temporal association of the development of oropharyngeal microbiota with early life wheeze in a population based birth cohort

Elizabeth Powell, Sara Fontanella, Eve Boakes, Daniella Belgrave, Alex G Shaw, Emma Cornwell, Roberto Fernandez-Crespo, Colin G Fink, Adnan Custovic, J Simon Kroll

E-Bio-Medicine 46 pp486-498, 2019

Viral and bacterial infection elicit distinct changes in plasma lipids in febrile children

Xinzhu Wang, Ruud Nijman, Stephane Camuzeaux, Caroline Sands, Heather Jackson, Myrsini Kaforou, Marieke Emonts, Jethro Herberg, Ian Maconochie, Enitan D Carrol, Stephane C Paulus, Werner Zenz, Michiel Van der Flier, Ronald de Groot, Federico Martinon-Torres, Luregn J Schlapbach, Andrew J Pollard, Colin Fink, Taco T Kuijpers, Suzanne Anderson, Matthew Lewis, Michael Levin, Myra McClure, on behalf of EUCLIDS consortium

Nature, 2019

2018

Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study

Boeddha NP, Klobassa DS, Secka F, Paulus S, de Groot R, Schlapbach LJ, Driessen GJ, Anderson ST, Emonts M, Zenz W, Carrol ED, Van der Flier M, Levin M; EUCLIDS Consortium

Lancet Child Adolesc Health. 2018 Jun;2(6):404-414 DOI: doi: 10.1016/S2352-4642(18)30113-5

Human Amylase gene copy number variation as a determinant of metabolic state

Elder J.D., Ramsden D.B., Burnett D., Weickert M.O., Barber T

Expert Review of Endocrinology and Metabolism, 2018 (13) 193-205

Comparison of the first whole genome sequence of Haemophilus quentini with two new strains of Haemophilus quentini and other species of Haemophilus

Hubbard A.T.M., Davies S.E.W., Baxter L., Thompson S, Collery M.M, Hand D.C, Thomas D.J .I, Fink C.G

Genome. 2018 May;61 (5):379-385 DOI: doi: 10.1139/gen-2017-0195

Mortality and morbidity in community-acquired sepsis in European paediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS)

Boeddha NP, Schlapbach LJ, Driessen GJ, Herberg JA, Rivero-Calle I, Cebey-López M, Klobassa DS, Philipsen R, de Groot R, Inwald DP, Nadel S, Paulus S, Pinnock E, Secka F, Anderson ST, Agbeko RS, Berger C, Fink CG, Carrol ED, Zenz W, Levin M, van der Flier M, Martinón-Torres F, Hazelzet JA, Emonts M; EUCLIDS consortium

Crit Care. 2018 May 31;22(1):143 DOI: doi: 10.1186/s13054-018-2052-7

Genetic diversity among white-nest swiftlets of the genus Aerodramus (Aves: Apodidae: Collocaliini) of house-farms in Malaysia

Goh W.L., Siew W.S., Davies S.E.W., Ball S., Khoo G., Lim C.K., Rahman M. A., Earl of Cranbrook

Raffles Bulletin of Zoology. 2018 June 22; (66):350–360

2016

Bacteremia in Children Hospitalized with Respiratory Syncytial Virus Infection

Miriam Cebey-López, Jacobo Pardo-Seco, Alberto Gómez-Carballa, Nazareth Martinón-Torres, José María Martinón-Sánchez, Antonio Justicia-Grande, Irene Rivero-Calle, Elli Pinnock, Antonio Salas, Colin Fink, Federico Martinón-Torres; GENDRES network

PLoS One, February 2016

Draft whole-genome sequence of a Haemophilus quentini strain isolated from an infant in the United Kingdom

Hubbard ATM, Davies SEW, Baxter L, Thompson S, Collery MM, Hand DC, Fink CG, Thomas DJI

Genome Announc 4(5):e01075-16, 2016

Does Viral Co-Infection Influence the Severity of Acute Respiratory Infection in Children?

Cebey-López M, Herberg J, Pardo-Seco J, Gómez-Carballa A, Martinón-Torres N, Salas A, Martinón-Sánchez JM, Justicia A, Rivero-Calle I, Sumner E, Fink C, Martinón-Torres F; GENDRES network

PLoS One. 2016 Apr 20;11(4):e0152481

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children

Herberg JA, Kaforou M, Wright VJ, Shailes H, Eleftherohorinou H, Hoggart CJ, Cebey-López M, Carter MJ, Janes VA, Gormley S, Shimizu C, Tremoulet AH, Barendregt AM, Salas A, Kanegaye J, Pollard AJ, Faust SN, Patel S, Kuijpers T, Martinón-Torres F, Burns JC, Coin LJ, Levin M; IRIS Consortium

JAMA. 2016 Aug 23-30;316(8):835-45