Rapid Diagnosis and Biomedical Research
Providing a clinically supported service for the rapid diagnosis and management of infectious and genetic disease.
2023
Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature
Dominic Habgood-Coote 1, Clare Wilson 1, Chisato Shimizu 2, Anouk M Barendregt 3, Ria Philipsen 4, Rachel Galassini 1, Irene Rivero Calle 5, Lesley Workman 6, Philipp K A Agyeman 7, Gerben Ferwerda 4, Suzanne T Anderson 8, J Merlijn van den Berg 3, Marieke Emonts 9, Enitan D Carrol 10, Colin G Fink 11, Ronald de Groot 4, Martin L Hibberd 12, John Kanegaye 2, Mark P Nicol 13, Stéphane Paulus 14, Andrew J Pollard 15, Antonio Salas 16, Fatou Secka 8, Luregn J Schlapbach 17, Adriana H Tremoulet 2, Michael Walther 8, Werner Zenz 18
Med. 2023 Sep 8;4(9):635-654.e5
A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study
Heather R Jackson*, Judith Zandstra*, Stephanie Menikou, Melissa Shea Hamilton, Andrew J McArdle, Roman Fischer, Adam M Thorne, Honglei Huang, Michael W Tanck, Machiel H Jansen, Tisham De, Philipp K A Agyeman, Ulrich Von Both, Enitan D Carrol, Marieke Emonts, Irini Eleftheriou, Michiel Van der Flier, Colin Fink, Jolein Gloerich, Ronald De Groot, Henriette A Moll, Marko Pokorn, Andrew J Pollard, Luregn J Schlapbach, Maria N Tsolia, Effua Usuf, Victoria J Wright, Shunmay Yeung, Dace Zavadska, Werner Zenz, Lachlan J M Coin, Climent Casals-Pascual, Aubrey J Cunnington, Federico Martinon-Torres, Jethro A Herberg, Marien I de Jonge†, Michael Levin†, Taco W Kuijpers†, Myrsini Kaforou†, on behalf of the PERFORM consortium‡
Lancet Digital Health: 2023, Vol 5: 11 pp e774–785
2022
Circadian rhythms in the plant host influence rhythmicity of rhizosphere microbiota
Amy Newman, Emma Picot, Sian Davies, Sally Hilton, Isabelle A. Carré and Gary D. Bending
BMC Biol 20, 235 (2022)
Diagnostic accuracy of multiplex respiratory pathogen panels for influenza or respiratory syncytial virus infections: systematic review and meta-analysis
Sophie Jullien, Felicity Fitzgerald, Suzanne Keddie, Oliver Baerenbold, Quique Bassat, John Bradley, Jane Falconer, Colin Fink, Ruth Keogh, Heidi Hopkins and Marie Voice
BMC Infectious Diseases (2022) 22:785
Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations
Vikrant Kumar, Richard B. Pouw, Matias I. Autio, Manfred G. Sagmeister, Zai Yang Phua, Lisa Borghini, Victoria J. Wright, Clive Hoggart, Bangfen Pan, Antson Kiat Yee Tan, Alexander Binder, Mieke C. Brouwer, Ellie Pinnock, Ronald De Groot, Jan Hazelzet, Marieke Emonts, Michiel Van Der Flier, Karl Reiter, Markus M. Nöthen, Per Hoffmann, EUCLIDS consortium, Luregn J. Schlapbach, Evangelos Bellos, Suzanne Anderson, Fatou Secka, Federico Martinón-Torres, Antonio Salas, Colin Fink, Enitan D. Carrol, Andrew J. Pollard, Lachlan J. Coin, Werner Zenz, Diana Wouters, Lay Teng Ang, Martin L. Hibberd, Michael Levin, Taco W. Kuijpers, and Sonia Davila
American Journal of Human Genetics. 2022 Sep 1; 109(9): 1680–1691
ISSN 0002-9297
Low levels of factor H family proteins during meningococcal disease indicate systemic processes rather than specific depletion by Neisseria meningitidis
van Beek, Anna E, Pouw, Richard B, Wright, Victoria J, Sallah, Neneh, Inwald, David, Hoggart, Clive, Brouwer, Mieke C, Galassini, Rachel, Thomas, John, Calvo-Bado, Leo A, Fink, Colin, Jongerius, Ilse, Hibberd, Martin, Wouters, Diana, Levin, Michael and Kuijpers, Taco W on behalf of the EUCLIDS Consortium
Frontiers in Immunology, 13-2022
ISSN 1664-3224
First report of black rot caused by Xanthomonas nasturtii onwatercress in Spain and Portugal
D. M. Lascelles1,2 M. R. Roberts2 L. Cruz3 J. Cruz3 D. J. Studholme4 J. Harrison4 S. F. Greer5 M. Grant5 J. M. Holden6 B. Carter7 A. Bryning7 S. Carroll7 A. Aspin7 J. G. Vicente5,7
New Dis Rep. 2022;46:e12134. DOI: https://doi.org/10.1002/ndr2.12134
The temporal pattern and lifestyle associations of respiratory virus infection in a cohort study spanning the first two years of life
Powell E, Sumner E, Shaw AG, Calvez R, Fink CG, Kroll JS
BMC Pediatr. 2022 Mar 31;22(1):166 DOI: doi: 10.1186/s12887-022-03215-3. PMID: 35361147
Comparing lateral flow testing with a rapid RT-PCR method for SARS-CoV-2 detection in the United Kingdom – A retrospective diagnostic accuracy study
Taylor A, Calvez R, Atkins M, Fink CG
Health Sci Rep. 2022;5:e811 DOI: doi:10.1002/hsr2.811
2021
Loss of Factor H family proteins associates with meningococcal disease severity
Anna E. van, Richard B. Pouw, Victoria J. Wright, Neneh Sallah, David Inwald, Clive Hoggart, Mieke C. Brouwer, Rachel Galassini, John Thomas, Leo Calvo-Bado, Colin Fink, Ilse Jongerius, Martin Hibberd, Diana Wouters, Michael Levin, Taco W. Kuijpers
2021
High-throughput sequencing reveals dietary segregation in Malaysian babblers
Mohammad Saiful Mansor, Fasihah Zarifah Rozali, Sian Davies, Shukor Md. Nor, Rosli Ramli
Current Zoology, 2021
Mechanisms Involved in the Active Secretion of CTX-M-15b-Lactamase by Pathogenic Escherichia coli ST131
Severine Rangama,a Ian D. E. A. Lidbury, a,b Jennifer M. Holden,a,c Chiara Borsetto, a Andrew R. J. Murphy, a Peter M. Hawkey,d Elizabeth M. H. Wellington
Rangama et al. 2021 Volume 65 Issue 10 e00663-21 Antimicrobial Agents and Chemotherapy
School of Life Sciences, University of Warwick, Coventry, United Kingdom
bDepartment of Animal and Plant Science, The University of Sheffield, Sheffield, United Kingdom
c Micropathology Ltd., University of Warwick Science Park, Coventry, United Kingdom
dInstitute of Microbiology and Infection, University of Birmingham, Edgbaston, United Kingdom