Pathogen Detection Services

We offer a comprehensive range of assays for the rapid detection of pathogens and host responses (see serology). We also offer viral load quantitation, genotyping and drug resistance typing for certain pathogens, please see the list below for details.

We will consider any project for the development of new molecular diagnostic assays, with the aim of improving the sensitivity or speed of diagnosis over existing methods.

All our laboratory diagnostic work is quality assured to Clinical Pathology Accreditation (CPA) standards.

Healthcare or other professional individuals/organisations are invited to discuss details of these services.

  • 16S rRNA bacterial gene: detection, quantitation and sequencing
  • 18S rRNA fungal gene detection and sequencing
  • Adenovirus (Q,T)
  • Acanthamoeba
  • Aspergillus genus
  • Bocavirus
  • Bordetella pertussis and Bordetella genus
  • Borrelia burgdorferi
  • Brucella genus
  • Candida albicans
  • Chlamydia pneumoniae
  • Chlamydia psittaci
  • Chlamydia trachomatis
  • Coronavirus 229E
  • Coronavirus OC43
  • Cryptococcus neoformans
  • Cytomegalovirus (Q)
  • Cytomegalovirus ganciclovir resistance
  • Enterovirus
  • Epstein Barr virus (Q)
  • Haemophilus ducreyi
  • Haemophilus influenzae/parainfluenzae
  • HBV drug resistance mutation screen
  • Hepatitis B virus (Q,T)
  • Hepatitis C virus (Q,T)
  • Hepatitis D virus
  • Hepatitis E virus
  • Herpes Simplex virus types 1 and 2 (T)
  • HIV-1 LTR, env, gag and pol genes
  • HIV-1 RNA (Q,T,R)
  • Human Herpesvirus 6 (Q)
  • Human Herpesvirus 7
  • Human Herpesvirus 8 (Q)
  • Human metapneumovirus
  • Influenza viruses (A and B)
  • Leptospira genus
  • Listeria monocytogenes
  • Measles virus
  • Mumps virus
  • Mycobacterium avium complex
  • Mycobacterium genus
  • Mycobacterium TB rifampicin resistance
  • Mycobacterium tuberculosis complex
  • Mycoplasma genitalium DNA
  • Mycoplasma genus
  • Mycoplasma pneumoniae
  • Neisseria gonorrhoeae
  • Neisseria meningitidis (T)
  • Papillomavirus (T)
  • Parainfluenza viruses (1,2,3,4)
  • Parechovirus
  • Parvovirus B19 (Q)
  • Pneumocystis carinii (aka jiroveci)
  • Polyoma BK virus (Q)
  • Polyoma JC virus
  • Propionibacteria/Actinomyces
  • Respiratory Syncytial virus
  • Rhinovirus
  • Rubella virus
  • Staphylococcus genus
  • Streptococcus group A
  • Streptococcus group B
  • Streptococcus pneumoniae
  • Toxoplasma gondii
  • Treponema pallidum
  • Trichomonas vaginalis
  • Tropheryma whippelii
  • Ureaplasma urealyticum/parvum DNA
  • Varicella Zoster virus
  • West Nile Fever virus

Key

  • ‘Q’: Quantitation
  • ‘T’: Typing or subtyping (see below)
  • ‘R’: Detection of drug resistance mutations (see below)

Notes

  • Adenovirus typing: Subgenus classification in all cases with specific type available in most.
  • Cytomegalovirus Gancilovir resistance: UL97 (codons 460-665) encoded resistance mutations only.
  • Hepatitis B virus: Classification of genotypes A to H. Screen of rt domain for the following resistance mutations: rtM204I/V (Lamivudine), rtV/G173L, rtV/L/M207I (Famciclovir), rtL180M (Lamivudine/Famciclovir), rtA181V/T, rtN236T (Adefovir) and rtI169T, rtT184G, rtS202I, rtM250V (Entecavir).
  • Hepatitis C virus: Classification of all genotypes/subtypes available in most cases.
  • HIV-1 Drug resistance: Complete screen of Protease (codons 1-99) and RT domains (codons 1-335).
  • Mycobacterium tuberculosis Rifampicin resistance: Screen of rpoB gene codons 479-580.
  • Neisseria meningitidis typing: Classification of types A,B,C,W&Y.
  • Papillomaviruses: Classification of all genotypes available in most cases.
  • Micropathology customers can access prices and turnaround times for these tests in the Customer Area.

N.B. Whilst we can only accept direct instructions from healthcare professionals, we are happy to provide information to individuals, so that personal physicians may be informed of our services.

New assays are constantly under development. If an organism of interest is not on the above list, please enquire.